In the second episode Paul meets 13-year-old Lola who has been in hospital for four weeks after being diagnosed with Juvenile Dermatomyositis which has caused inflammation of her muscles and skin. When Paul meets Lola her muscles are so weak and she can't walk, but her mum explains that just six weeks earlier she had been fine. The condition affects one in a million people and Lola needs physiotherapy to help her. Paul is there when Lola tried to take some steps for the first time in two months.

Also in the programme, Paul meets ten-year-old Oscar who has Tourette's. Oscar mostly has motor ticks, which means he sniffs and coughs. He explains that it's a human glitch which causes him to have involuntary movements. But he tells Paul that after developing Tourette's he became too anxious to leave the house.